Results of research of efficacy and tolerability of lamitor (lamotrigine) in the treatment of idiopathic focal and generalized forms of epilepsy as monotherapy or in polytherapy in children and adolescents are presented. 25 patients were included in our research, aged from 2 till 18 years, with idiopathic focal (n=10) and generalized (n=15) epilepsy, which received lamitor in monotherapy (5 patients) or in polytherapy (20 patients). As a whole, remission was reached at 18 of 25 patients (72%), significant improvement – at 5 of 25 (20%), the effect was absent – 1 patient (4%), deterioration was noted only in 1 case (4%). Efficiency of lamitor in dependence on epilepsy form was considered. Good tolerability of lamitor is noted. Thus, our research demonstrated high efficiency and good tolerability of lamitor as an additional antiepileptic drug and in monotherapy in the treatment of idiopathic epilepsies in children and adolescents.

The author proposed a review of literature devoted to extrapyramidal movement disorders (hyperkinesis) as manifestation of various diseases at children. The aspects of pathogenesis and neurochemistry, clinical manifestations of extrapyramidal movement disorders, their diagnostics and evolution in the course of diseases are considered. The author presented also this own observations: hyperkinesis as manifestation of various mental and neurologic diseases in a group of 310 children and features of evolution hyperkinesis in process of disease development are considered

The authors proposed a detailed review of literature devoted to myoclonic astatic epilepsy (Doose syndrome). The authors describe the history of study of myoclonic astatic epilepsy, its prevalence, etiology and the role of genetic factors, clinical pictures, including the main type of seizures, diagnostic criteria and nosology. The characteristics of EEG and neuroimaging are prescribed, and also differential diagnosis, approaches to treatment and prognosis.

Уильям Уилки Коллинз (1824-1889 гг) – основоположник «сенсационного романа» (в дальнейшем разделившегося на приключенческий и детективный роман), признанный мастер интриги и увлекательного сюжета. За свою творческую жизнь он создал около 30 романов, более 60 коротких историй, 14 пьес и более 100 документальных статей. Он был близким другом Чарльза Диккенса с момента из встречи в марте 1851 г. и на протяжении всей жизни. Спустя 150 лет его романы сохраняют широкую известность во всем мире и переведены на многие языки. Интересно, что в книгах этого автора прослеживается его интерес к науке, и особенно к медицине. В произведениях Уилки Коллинз можно встретить описание посттравматической эпилепсии, клинические эффекты опиума, переживания людей с чувствительными расстройствами, включая слепоту и глухоту. Автор проявляет интерес к лечению заболеваний психики и нервной системы, в том числе, к применению музыкотерапии при данных расстройствах (Seagal S., 1983; Miranda C.M., 2011).