Larisa V. Kalinina was born on 7 January, 1927 in Sukhumi, Georgian SSR, in the military family.

In 1944, due to her father’s work, the family moved to Vilnius, Lithuanian SSR where she finished the secondary school (1945). The same year L.V. Kalinina entered the medical faculty of the Vilnius state university, from which she successfully graduated with a qualification of Medical Doctor in 1950.

The first three years after university (1950-1953) she worked as a pediatrician at the children’s city hospital in Vilnius. Then the family moved to Moscow, where she continued to work as a pediatrician at the policlinics. In 1956-1958, she had her postgraduate studies at the department of neurology, children’s city hospital №1 (Morozov children’s city hospital). For a few time she worked as a senior registrar until she was invited to be the head of the department of neurological disorders, children’s city hospital №1. In 1958-1964, she took this position. At the same time (1959-1964) she began her pedagogical activity and taught neurology at her department. Among her pupils were students of the medical school.

In 1964 she joins the department of neurological disorders of the Pediatric faculty, N.I. Pirogov Medical University, which was founded at that time and run by professor Levon Oganesovich Badalyan. Since 1964 she has worked at this department where she consistently took the positions of assistant (1964-1967), associate professor (1967-1974) and professor (since 1974 till present). Nowadays this department is named as the department of neurology, neurosurgery and medical genetics at the Pediatric faculty of the N.I. Pirogov Medical University.

In 1967, she successfully defended her master's degree entitled "Basal arachnoiditis in children" and in 1973 - her doctoral thesis entitled "Congenital cerebrovascular anomalies in children ".

In the 1970s, paralleled with her work at the department, L.V. Kalinina took the position of a senior researcher at the academic group headed by Yu.M. Lopukhin at the Cardiovascular Research Institute.

Since 1982 she was a scientific secretary of the specialized academic council at the N.I. Pirogov Medical University, as well as a member of several critical commissions at the University, the Ministry of Health of the RSFSR, the Ministry of Health of the USSR.

In 1987-2010, she was the Principal External Child Specialist in Neurology at the Department of Health of Moscow.

She was honored by the Ministry of Health of the USSR and awarded the medal “For the contribution to the country” in 2003.

L.V. Kalinina made significant contribution to such current problems in pediatric neurology as neuroinfections, congenital and inherited disorders of the nervous system, acute cerebral circulatory disorders in children, epilepsy and paroxysmal events, neurorehabilitation.

L.V. Kalinina is an author of more than 200 scientific works. Among them are the following training manuals and monographs:

«Guide to research techniques in neuroscience», Moscow, 1968 (co-author L.O. Badalyan, etc.)

«Genetic diseases in children», Tashkent: Medicine, 1980 (co-author L.O. Badalyan, etc.)

«Inherited metabolic disorders and phakomatoses», Moscow: Medicine, 1981 (co-author E.I. Gusev)

«Hydrocephaly and thymomegaly», Baku: Azgosizdat, 1992 (co-authors T.K. Kadyrova, O.A. Kasimova, А.А. Mekhtiyeva, S. Sultanova)