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Русский журнал детской неврологии

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Хирургическое лечение эпилепсии у пациентов с туберозным склерозом

https://doi.org/10.17650/2073-8803-2015-1-40-46

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Аннотация

За немногим исключением, у пациентов с туберозным склерозом (ТС) и резистентной к медикаментозному лечению эпилепсией эпилептогенные очаги поражения потенциально присутствуют в обоих полушариях. Еще 10 лет назад это рассматривалось как критерий исключения в отношении хирургического лечения. Однако накопленный опыт показал, что среди этой группы пациентов немало случаев, когда источником эпилептических приступов на протяжении многих лет служит только один очаг. Такие пациенты могут рассматриваться как кандидаты для хирургического лечения эпилепсии. Дальнейшая разработка многоэтапного метода обследования у пациентов с билатеральным поражением произвела практически революцию – получены обнадеживающие результаты в отношении прогноза ремиссии приступов после операции. Также с появлением новых знаний в этой области все чаще становится возможным дифференцировать эпилептогенные и неэпилептогенные очаги неинвазивными методами. Наиболее важное достижение в хирургическом лечении эпилепсии при туберозном склерозе состоит в том, что раннее хирургическое вмешательство способно предотвратить развитие тяжелой умственной отсталости, которая часто является основным фактором, снижающим качество жизни членов семьи пациента с ТС.

Об авторах

Hans Holthausen
Neuropediatric Clinic and Clinic for Neurorehabiltation, Epilepsy Center for Children and Adolescents; Schoen-Klinik Vogtareuth; 20 Krankenhausstrasse, D-83569, Vogtareuth, Deutschland
Россия


Tom Pieper
Neuropediatric Clinic and Clinic for Neurorehabiltation, Epilepsy Center for Children and Adolescents; Schoen-Klinik Vogtareuth; 20 Krankenhausstrasse, D-83569, Vogtareuth, Deutschland
Россия


Hans Eitel
Neuropediatric Clinic and Clinic for Neurorehabiltation, Epilepsy Center for Children and Adolescents; Schoen-Klinik Vogtareuth; 20 Krankenhausstrasse, D-83569, Vogtareuth, Deutschland
Россия


Manfred Kudernatsch
Neurosurgery Clinic and Clinic for Epilepsy Surgery; Schoen-Klinik Vogtareuth; 20 Krankenhausstrasse, D-83569, Vogtareuth, Deutschland
Россия


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Для цитирования:


Holthausen H., Pieper T., Eitel H., Kudernatsch M. Хирургическое лечение эпилепсии у пациентов с туберозным склерозом. Русский журнал детской неврологии. 2015;10(1):40-46. https://doi.org/10.17650/2073-8803-2015-1-40-46

For citation:


Holthausen H., Pieper T., Eitel H., Kudernatsch M. EPILEPSY SURGERY IN PATIENTS WITH TUBEROUS SCLEROSIS. Russian Journal of Child Neurology. 2015;10(1):40-46. (In Russ.) https://doi.org/10.17650/2073-8803-2015-1-40-46

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ISSN 2073-8803 (Print)
ISSN 2412-9178 (Online)