An acute hemorrhagic leukoencephalitis (clinical case)

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Abstract

Hurst’s disease (acute hemorrhagic leukoencephalitis) is a rare fulminant demyelinating disease of the central nervous system. It was singled out as a separate nosological form in the middle of the 20th century. The etiology is not fully understood. According to statistics, the disease most often occurs after a viral or bacterial infection. Patients have an increase in body temperature up to febrile values, headaches, gastrointestinal disorders, cognitive impairments. When making a diagnosis, they are guided by the results of neuroimaging (computed tomography/magnetic resonance imaging), analysis of cerebrospinal fluid, and brain biopsy. Corticosteroids, acyclovir, antibiotics, immunoglobulins, plasmapheresis are used for treatment. The prognosis in patients with acute hemorrhagic leukoencephalitis is poor.

About the authors

Е. А. Kulish

Serpukhov Central District Hospital

Email: fake@neicon.ru
ORCID iD: 0000-0001-7647-1667

3 Forssa St., Serpukhov142200

Russian Federation

V. М. Frolova

M.F. Vladimirsky Moscow Regional Research Clinical Institute

Author for correspondence.
Email: victoriafroloff@yandex.ru
ORCID iD: 0000-0002-1816-7904

Build. 1, 61/2 Shchepkina St., Moscow 129110

Russian Federation

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