An acute hemorrhagic leukoencephalitis (clinical case)
- Authors: Kulish Е.А.1, Frolova V.М.2
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Affiliations:
- Serpukhov Central District Hospital
- M.F. Vladimirsky Moscow Regional Research Clinical Institute
- Issue: Vol 18, No 4 (2023)
- Pages: 49-52
- Section: CLINICAL OBSERVATIONS
- Published: 03.01.2024
- URL: https://rjdn.abvpress.ru/jour/article/view/452
- DOI: https://doi.org/10.17650/2073-8803-2023-18-4-49-52
- ID: 452
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Abstract
Hurst’s disease (acute hemorrhagic leukoencephalitis) is a rare fulminant demyelinating disease of the central nervous system. It was singled out as a separate nosological form in the middle of the 20th century. The etiology is not fully understood. According to statistics, the disease most often occurs after a viral or bacterial infection. Patients have an increase in body temperature up to febrile values, headaches, gastrointestinal disorders, cognitive impairments. When making a diagnosis, they are guided by the results of neuroimaging (computed tomography/magnetic resonance imaging), analysis of cerebrospinal fluid, and brain biopsy. Corticosteroids, acyclovir, antibiotics, immunoglobulins, plasmapheresis are used for treatment. The prognosis in patients with acute hemorrhagic leukoencephalitis is poor.
About the authors
Е. А. Kulish
Serpukhov Central District Hospital
Email: fake@neicon.ru
ORCID iD: 0000-0001-7647-1667
3 Forssa St., Serpukhov142200
Russian FederationV. М. Frolova
M.F. Vladimirsky Moscow Regional Research Clinical Institute
Author for correspondence.
Email: victoriafroloff@yandex.ru
ORCID iD: 0000-0002-1816-7904
Build. 1, 61/2 Shchepkina St., Moscow 129110
Russian FederationReferences
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