Neuromyelitis optica spectrum disorder in childhood (a case report)
https://doi.org/10.17650/2073-8803-2017-12-4-56-62
Abstract
Neuromyelitis optica spectrum disorder is an inflammatory demyelinating disease of the central nervous system with selective damage to the optic nerves and spinal cord. The clinical case of a child 11 years old and its course throughout the year, with an onset in the form of an episode of visual impairment with signs of a previously developed partial atrophy of the optic nerves of both eyes and a manifestation of retrobulbar neuritis on the left eye is considered in the article. Repeatedly conducted magnetic resonance examination revealed a pattern of focal lesion of the left and then of the right optic nerve with a violation of the integrity of the blood brain barrier and an extended focus in the structure of the spinal cord of the cervical spine. The blood test for antibody to aquaporin-4 was positive. Optical coherence tomography revealed decrease in the thickness of the peripapillary fibers of the retina in all quadrants in both eyes, which indicates a partial atrophy of the optic nerves of both eyes, as a result of repeatedly transferred retrobulbar neuritis in both eyes.
About the Authors
A. S. Kotov
M.F. Vladimirsky Moscow Regional Research Clinical Institute.
Russian Federation
61/2 Shchepkina St., Moscow 129110.
Russian Federation
61/2 Shchepkina St., Moscow 129110.
Yu. V. Tokareva
M.F. Vladimirsky Moscow Regional Research Clinical Institute.
Russian Federation
61/2 Shchepkina St., Moscow 129110.
Russian Federation
61/2 Shchepkina St., Moscow 129110.
V. N. Lutsik
M.F. Vladimirsky Moscow Regional Research Clinical Institute.
Russian Federation
61/2 Shchepkina St., Moscow 129110.
Russian Federation
61/2 Shchepkina St., Moscow 129110.
M. V. Panteleeva
M.F. Vladimirsky Moscow Regional Research Clinical Institute.
Russian Federation
61/2 Shchepkina St., Moscow 129110.
Russian Federation
61/2 Shchepkina St., Moscow 129110.
A. V. Shatalin
M.F. Vladimirsky Moscow Regional Research Clinical Institute.
Russian Federation
61/2 Shchepkina St., Moscow 129110.
Russian Federation
61/2 Shchepkina St., Moscow 129110.
E. V. Mukhina
M.F. Vladimirsky Moscow Regional Research Clinical Institute.
Russian Federation
61/2 Shchepkina St., Moscow 129110.
Russian Federation
61/2 Shchepkina St., Moscow 129110.
M. S. Bunak
M.F. Vladimirsky Moscow Regional Research Clinical Institute.
Russian Federation
61/2 Shchepkina St., Moscow 129110.
Russian Federation
61/2 Shchepkina St., Moscow 129110.
O. M. Andryukhina
M.F. Vladimirsky Moscow Regional Research Clinical Institute.
Russian Federation
61/2 Shchepkina St., Moscow 129110.
Russian Federation
61/2 Shchepkina St., Moscow 129110.
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Review
For citations:
Kotov A.S., Tokareva Yu.V., Lutsik V.N., Panteleeva M.V., Shatalin A.V., Mukhina E.V., Bunak M.S., Andryukhina O.M. Neuromyelitis optica spectrum disorder in childhood (a case report). Russian Journal of Child Neurology. 2017;12(4):56-62. (In Russ.) https://doi.org/10.17650/2073-8803-2017-12-4-56-62
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