NEUROFIBROMATOSIS TYPE 1 OR GIANT MELANOCYTIC NEVUS: PROBLEMS OF DIAGNOSTIC

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Abstract

Neurofibromatosis type 1 (NF-1) is a hereditary disease mainly affecting skin and peripheral nervous system. Individual signs of cutaneous manifestations of NF-1 can imitate or be combined with other neurocutaneous syndromes. At present on the outpatient phase is not always possible to conduct a detailed examination of the patients with NF-1 and to determine the indications for modern diagnostic examination in a specialized hospital. It can be important to verify the diagnosis. The authors presented short review of russian and foreign literature and clinical case of the patient with a specific lesion of the skin against the background of congenital giant melanocytic nevus. Problems of differential diagnosis of NF-1 and congenital giant pigmented nevus were analyzed.

About the authors

A. S. Ol’shanskaya

Krasnoyarsk State Medical University named after V.F. Voino-Yasenetsky, Ministry of Health of Russia

Author for correspondence.
Email: annaolsh@mail.ru
1 Partizan Zheleznyak Str., Krasnoyarsk 660022 Russian Federation

A. V. Dyuzhakova

Krasnoyarsk State Medical University named after V.F. Voino-Yasenetsky, Ministry of Health of Russia

Email: fake@neicon.ru
1 Partizan Zheleznyak Str., Krasnoyarsk 660022 Russian Federation

I. P. Artyukhov

Krasnoyarsk State Medical University named after V.F. Voino-Yasenetsky, Ministry of Health of Russia

Email: fake@neicon.ru
1 Partizan Zheleznyak Str., Krasnoyarsk 660022 Russian Federation

N. A. Shnayder

Krasnoyarsk State Medical University named after V.F. Voino-Yasenetsky, Ministry of Health of Russia

Email: fake@neicon.ru
1 Partizan Zheleznyak Str., Krasnoyarsk 660022 Russian Federation

D. V. Dmitrenko

Krasnoyarsk State Medical University named after V.F. Voino-Yasenetsky, Ministry of Health of Russia

Email: fake@neicon.ru
1 Partizan Zheleznyak Str., Krasnoyarsk 660022 Russian Federation

Yu. V. Karacheva

Krasnoyarsk State Medical University named after V.F. Voino-Yasenetsky, Ministry of Health of Russia

Email: fake@neicon.ru
1 Partizan Zheleznyak Str., Krasnoyarsk 660022 Russian Federation

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