ГЕНЕТИКА АУТИЗМА (ОБЗОР ЗАРУБЕЖНОЙ ЛИТЕРАТУРЫ)
https://doi.org/10.17650/2073-8803-2013-8-3-31-45
Аннотация
Аутизм может встречаться при хромосомных и генетических синдромах, пороках развития головного мозга, болезнях обмена и др. В связи с этим в настоящее время принят термин «атипичный» или «синдромальный» аутизм – аутизм, являющийся одним из симптомов другого заболевания. Генетические и хромосомные причины составляют 25-50% случаев аутизма. Авторы представили подробный обзор литературы, посвященный генетическим аспектам аутизма. В статье рассматриваются известные наследственные заболевания, проявляющиеся аутизмом, классификации генов-кандидатов аутизма, теории патогенеза аутизма, подходы к диагностике, а также проблемы, связанные с генетическим консультированием при диагностике аутизма.
Об авторах
М. Ю. Бобылова
Институт детской неврологии и эпилепсии им. Святителя Луки, Москва
Россия
Россия
Н. Л. Печатникова
Российская детская клиническая больница; кафедра неврологии, нейрохирургии и медицинской генетики педиатрического факультета РНИМУ, Москва
Россия
Россия
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Рецензия
Для цитирования:
Бобылова М.Ю., Печатникова Н.Л. ГЕНЕТИКА АУТИЗМА (ОБЗОР ЗАРУБЕЖНОЙ ЛИТЕРАТУРЫ). Русский журнал детской неврологии. 2013;8(3):31-45. https://doi.org/10.17650/2073-8803-2013-8-3-31-45
For citation:
Bobylova M.Yu., Petchatnikova H.L. GENETICS OF AUTISTIC DISORDER (REVIEW OF FOREIGN LITERATURE). Russian Journal of Child Neurology. 2013;8(3):31-45. (In Russ.) https://doi.org/10.17650/2073-8803-2013-8-3-31-45
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