ПРИМЕНЕНИЕ НОВОГО АНТИЭПИЛЕПТИЧЕСКОГО ПРЕПАРАТА — ЗОНЕГРАН (ЗОНИСАМИД) — В ЛЕЧЕНИИ ЭПИЛЕПСИИ (ОБЗОР ЛИТЕРАТУРЫ)
Аннотация
Несмотря на значительные успехи, достигнутые в эпилептологии, резистентные эпилепсии составляют примерно 30% среди всех форм эпилепсии. Представлен обзор современной литературы, посвященный эффективности и безопасности нового антиэпилептического препарата зонегран (зонисамид) в лечении эпилепсии. Рассмотрен механизм действия, особенности фармакокинетики, эффективность и переносимость зонисамида при резистентной фокальной эпилепсии, а также при других типах приступов и формах эпилепсии. Рассматриваются возможности применения зонисамида при коморбидных состояниях.
Ключевые слова
Об авторах
О. А. Пылаева
Институт детской неврологии и эпилепсии имени Святителя Луки, Москва
Россия
Россия
К. Ю. Мухин
Институт детской неврологии и эпилепсии имени Святителя Луки, Москва
Россия
Россия
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Для цитирования:
Пылаева О.А., Мухин К.Ю. ПРИМЕНЕНИЕ НОВОГО АНТИЭПИЛЕПТИЧЕСКОГО ПРЕПАРАТА — ЗОНЕГРАН (ЗОНИСАМИД) — В ЛЕЧЕНИИ ЭПИЛЕПСИИ (ОБЗОР ЛИТЕРАТУРЫ). Русский журнал детской неврологии. 2012;7(2):13-34. https://doi.org/10.17650/2073-8803-2012-7-2-13-34
For citation:
Pylaeva O.A., Мukhin K.Yu. A NEW ANTIEPILEPTIC DRUG — ZONEGRAN (ZONISAMIDE) — IN THE TREATMENT OF EPILEPSY (A REVIEW). Russian Journal of Child Neurology. 2012;7(2):13-34. (In Russ.) https://doi.org/10.17650/2073-8803-2012-7-2-13-34
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