Angiocentric glioma: clinical, pathomorphological and neuroradiological features of a rare epileptogenic tumor (a review and clinical case)
https://doi.org/10.17650/2073-8803-2024-19-3-51-59
Abstract
Angiocentric glioma is an extremely rare low-grade neuroepithelial tumor introduced into the World Health Organization classification of tumors of the central nervous system in 2007. Microscopically, it is a cluster of monomorphic bipolar cells with a predominant diffuse growth pattern and focal perivascular aggregation of tumor cells around blood vessels, which forms a specific angiocentric pattern. Despite the fact that a little more than 100 cases of detection of angiocentric glioma have been described in the literature, a number of clinical, pathomorphological and radiological criteria specific for this tumor have been identified that are characteristic long-term epilepsy associated tumors. The article presents the experience of complex, interdisciplinary diagnosis of angiocentric glioma in a child with focal structural epilepsy and a review of the literature. It should be noted that this is the first case of describing pathomorphologically confirmed angiocentric glioma on the territory of the Russian Federation.
About the Authors
V. S. Khalilov
Federal Research and Clinical Center for Children and Adolescents, Federal Medical and Biological Agency of Russia; Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
Varis Sadrutdinovich Khalilov
20 Moskvorechye St., Moscow 115409
1 Ostrovityanova St., 117997 Moscow
A. N. Kislyakov
Morozov Children’s City Clinical Hospital, Moscow Healthcare Department
Russian Federation
Russian Federation
1/9 4-yy Dobryninskiy Pereulok, Moscow
O. A. Ryleva
N.N. Burdenko National Scientific and Practical Center for Neurosurgery, Ministry of Health of Russia
Russian Federation
Russian Federation
16, 4-ya Tverskaya-Yamskaya St., Moscow 125047
N. A. Medvedeva
Federal Research and Clinical Center for Children and Adolescents, Federal Medical and Biological Agency of Russia; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Russian Federation
Russian Federation
20 Moskvorechye St., Moscow 115409
Build. 2, 8 Trubetskaya St., Moscow 119991
A. A. Kholin
Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
1 Ostrovityanova St., 117997 Moscow
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Review
For citations:
Khalilov V.S., Kislyakov A.N., Ryleva O.A., Medvedeva N.A., Kholin A.A. Angiocentric glioma: clinical, pathomorphological and neuroradiological features of a rare epileptogenic tumor (a review and clinical case). Russian Journal of Child Neurology. 2024;19(3):51-59. (In Russ.) https://doi.org/10.17650/2073-8803-2024-19-3-51-59
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