Preview

Russian Journal of Child Neurology

Advanced search

Balo’s concentric sclerosis: nosological affiliation, diagnostic criteria and treatment approaches Lecture with a description of a clinical case

https://doi.org/10.17650/2073-8803-2024-19-3-33-37

Abstract

Balo's concentric sclerosis, a rare demyelinating disease of the central nervous system with the formation of concentric areas of demyelination in the white matter of the brain, was previously classified as an atypical form of multiple sclerosis with a fulminant course and a poor prognosis. However, recent clinical observations have cast doubt on this statement. To date, it has been established that the outcomes of the disease can vary from complete recovery to significant disability or death. The classification of Balo's concentric sclerosis as a distinct disease or form of multiple sclerosis remains a matter of debate. The article describes a clinical case of a 29-year-old female patient with Balo's concentric sclerosis. A description of nosological data, diagnostic criteria, and approaches to therapy is provided.

About the Authors

A. A. Benidze
Medical and Rehabilitation Center “Dubna”, Federal Scientific and Clinical Center for Medical Rehabilitation and Balneology of the Federal Medical and Biological Agency of Russia
Russian Federation

Anna Alekseevna Benidze

5 Pravdy St., Dubna 141981



A. S. Kotov
M.F. Vladimirsky Moscow Regional Research Clinical Institute
Russian Federation

61/2 Shchepkina St., Moscow 129110



References

1. Jolliffe E.A., Guo Y., Hardy T.A. et al. Clinical and radiologic features, pathology, and treatment of Balo concentric sclerosis. Neurology 2021;97(4):e414–22. DOI: 10.1212/WNL.0000000000012230.

2. Keegan M., König F., McClelland R. et al. Relation between humoral pathological changes in multiple sclerosis and response to therapeutic plasma exchange. Lancet 2005;366(9485):579–82. DOI: 10.1016/S0140-6736(05)67102-4

3. Lukies M. Balo concentric sclerosis. Case study. Radiopaedia.org. DOI: 10.53347/rID-53875

4. Purohit B., Ganewatte E., Schreiner B., Kollias S. Balo’s concentric sclerosis with acute presentation and co-existing multiple sclerosistypical lesions on MRI. Case Rep Neurol 2015;7(1):44–50. DOI: 10.1159/000380813

5. Southin J.C., Avula S., du Plessis D. et al. Balo’s concentric sclerosis presenting asymptomatically in a child: clinicoradiological-pathological correlation. BMJ Case Rep 2023;16(11):e256185. DOI: 10.1136/bcr-2023-256185

6. Stadelmann C., Ludwin S., Tabira T. et al. Tissue preconditioning may explain concentric lesions in Balo’s type of multiple sclerosis. Brain 2005;128(Pt 5):979–87. DOI: 10.1093/brain/awh457

7. Vickaryous K., Poli De Frias F., Gonzalez G.A. A rare case of a Balo’s concentric sclerosis-like lesion in a young adult woman. Cureus 2023;15(10):e46803. DOI: 10.7759/cureus.46803

8. Wallner-Blazek M., Rovira A., Fillipp M. et al. Atypical idiopathic inflammatory demyelinating lesions: prognostic implications and relation to multiple sclerosis. J Neurol 2013;260(8):2016–22. DOI: 10.1007/s00415-013-6918-y

9. Weinshenker B.G., O’Brien P.C., Petterson T.M. et al. A randomized trial of plasma exchange in acute central nervous system inflammatory demyelinating disease. Ann Neurol 1999;46(6):878–86. DOI: 10.1002/1531-8249(199912)46:6<878::aid-ana10>3.0.co;2-q

10. Xie J.S., Jeeva-Patel T., Margolin E. Balo’s concentric sclerosis – a rare entity within the spectrum of demyelinating diseases. J Neurol Sci 2021;428:117570. DOI: 10.1016/j.jns.2021.117570


Review

For citations:


Benidze A.A., Kotov A.S. Balo’s concentric sclerosis: nosological affiliation, diagnostic criteria and treatment approaches Lecture with a description of a clinical case. Russian Journal of Child Neurology. 2024;19(3):33-37. (In Russ.) https://doi.org/10.17650/2073-8803-2024-19-3-33-37

Views: 261


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2073-8803 (Print)
ISSN 2412-9178 (Online)