Sleep disorder in Angelman syndrome: causes, mechanisms and methods of correction. Literature review
https://doi.org/10.17650/2073-8803-2022-17-3-55-62
Abstract
Sleep disorder is one of the prominent manifestations of Angelman syndrome. The exact causes are unknown and methods of correction are difficult. The literature review is devoted to studies of the pathogenesis of sleep disorders in Angelman syndrome (the effects of gene function in 15q11–q13 deletion, findings in polysomnography, video-EEG sleep monitoring, laboratory data), on the basis of which recommendations for the correction of dyssomnia, including methods of behavioral therapy, are given.
About the Authors
A. A. Psyanchin
Clinical Hospital “Mother and Child”
Russian Federation
Russian Federation
4 Lesnoy Proezd, Ufa 450071
M. Yu. Bobylova
Svt. Luka’s Institute of Child Neurology and Epilepsy; Svt. Luka’s Institute of Pediatric and Adult Neurology and Epilepsy
Russian Federation
Russian Federation
Mariya Yuryevna Bobylova
5 Nagornaya St., Troitsk, Moscow 108842
9 Akad. Anokhina St., Moscow 119571
T. Z. Yakupov
Clinical Hospital “Mother and Child”
Russian Federation
Russian Federation
5 Nagornaya St., Troitsk, Moscow 108842
9 Akad. Anokhina St., Moscow 119571
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Review
For citations:
Psyanchin A.A., Bobylova M.Yu., Yakupov T.Z. Sleep disorder in Angelman syndrome: causes, mechanisms and methods of correction. Literature review. Russian Journal of Child Neurology. 2022;17(3):55-62. (In Russ.) https://doi.org/10.17650/2073-8803-2022-17-3-55-62
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