Sleep disorder in Angelman syndrome: causes, mechanisms and methods of correction. Literature review

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Abstract

Sleep disorder is one of the prominent manifestations of Angelman syndrome. The exact causes are unknown and methods of correction are difficult. The literature review is devoted to studies of the pathogenesis of sleep disorders in Angelman syndrome (the effects of gene function in 15q11–q13 deletion, findings in polysomnography, video-EEG sleep monitoring, laboratory data), on the basis of which recommendations for the correction of dyssomnia, including methods of behavioral therapy, are given.

About the authors

A. A. Psyanchin

Clinical Hospital “Mother and Child”

Email: fake@neicon.ru

4 Lesnoy Proezd, Ufa 450071

Russian Federation

M. Yu. Bobylova

Svt. Luka’s Institute of Child Neurology and Epilepsy; Svt. Luka’s Institute of Pediatric and Adult Neurology and Epilepsy

Author for correspondence.
Email: mariya_bobylova@mail.ru
ORCID iD: 0000-0001-6125-0618

Mariya Yuryevna Bobylova 

5 Nagornaya St., Troitsk, Moscow 108842

9 Akad. Anokhina St., Moscow 119571

Russian Federation

T. Z. Yakupov

Clinical Hospital “Mother and Child”

Email: fake@neicon.ru

5 Nagornaya St., Troitsk, Moscow 108842

9 Akad. Anokhina St., Moscow 119571

Russian Federation

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