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Mental disorders in children with intractable epilepsy as a manifestation of forced normalization of the electroencephalogram (Landolt syndrome)

https://doi.org/10.17650/2073-8803-2018-13-4-70-74

Abstract

The forced normalization of the electroencephalogram (Landolt syndrome) is a rapid normalization of the electroencephalogram (decrease in or disappearance of paroxysmal activity) under the influence of anticonvulsant treatment of epilepsy patients, corresponding to a decrease in frequency or complete disappearance of seizures with the appearance of neuropsychiatric disorders (dysphorias, the syndrome of hyperactivity and attention deficit, mysophobia etc). The authors present a review of the literature on the Landolt syndrome, and own data.

About the Authors

D. A. Gagara
Republican Epilepsy Center, Republican Children’s Clinical Hospital, Ministry of Health of the Donetsk Republic.
Russian Federation
14 Bulvar Shakhtostroiteley, Donetsk 238052.


S. K. Evtushenko
M. Gorky Donetsk National Medical University.
Russian Federation

Department of Pediatric and General Neurology.

16 Prospekt Ilyicha, Donetsk 83003. 



References

1. Evtushenko S.K., Omelyanenko A.A. Clinical electroencephalography in children. Guideline for physicians. Donetsk: Donechchina, 2005. 860 p. (In Russ.).

2. Evtushenko S.K. Destructive and intractable forms of epilepsy and epileptic encephalopathy in children. Mezhdunarodniy nevrologicheskiy zhurnal = International Neurological Journal 2012;6(52):15–26. (In Russ.).

3. Mukhin K.Yu., Petrukhin A.S., Mironov M.B. Epileptic syndromes. Diagnosis and treatment. guideline for physicians. Moscow: Sistemnye resheniya, 2008. 223 p. (In Russ.).

4. Petrukhin A.S. Pediatric epileptology. Moscow: Meditsina, 2000. 623 p. (In Russ.).

5. Pylaeva O.A., Mukhin K.Yu., Petrukhin A.S. Side effects of antiepileptic medication. Moscow: Granat, 2016. 232 p. (In Russ.).

6. Bédard A.C., Schulz K.P., Cook E.H.Jr. еt al. Dopamine transporter gene variation modulates activation of striatum in youth with ADHD. Neuroimage 2010;53(3):935–42. DOI: 10.1016/j.neuroimage.2009.12.041.

7. Doose A. EEG in childhood epilepsy. Germany, 2005. 405 p.

8. Kim B., Koo M., Jun J. et al. Association between dopamine D4 receptor gene poly morphism and scores on a continuous performance test in korean children with attention deficit hyperactivity disorder. Psychiatry Investig 2009;6(3):216–21. DOI: 10.4306/pi.2009.6.3.216.

9. Landolt H. Some clinical electroencephalographical correlations in epileptic psychoses (twilight states). Electroencephalogr Clin Neurophysiol 1953;5:121–30.

10. Landolt H. Psychic disorders in epilepsy. Clinical and electroencephalographic research. Dtsch Med Wochenschr 1962;87:446–52.

11. Loganathan M.A., Enja M., Lippmann S. Forced normalization: epilepsy and psychosis interaction. Innov Clin Neurosci 2015;12(5–6):38–41.

12. Romanos M., Weise D., Schliesser M. et al. Structural abnormality of the substantia nigra in children with attentiondeficit hyperactivity disorder. Psychiatry Neurosci 2010;35(1):55–8.

13. Trimble M.R. The psychosis of epilepsy. New York: Raven Press, 1991. 224 p.


Review

For citations:


Gagara D.A., Evtushenko S.K. Mental disorders in children with intractable epilepsy as a manifestation of forced normalization of the electroencephalogram (Landolt syndrome). Russian Journal of Child Neurology. 2018;13(4):70-74. (In Russ.) https://doi.org/10.17650/2073-8803-2018-13-4-70-74

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ISSN 2073-8803 (Print)
ISSN 2412-9178 (Online)