Comorbidity between epilepsy and autism from the point of view of ontogenesis
https://doi.org/10.17650/2073-8803-2018-13-4-40-52
Abstract
Early childhood autism, or autism spectrum disorders, is an extremely heterogeneous group of conditions that share similar symptoms of dysontogenesis. Epilepsy is the most significant comorbidity in autism. The present article covers various aspects of comorbidity between epilepsy and autism, described in the literature over the last 50 years. This review aims to analyze the development of epilepsy and autism during ontogenesis and to identify causal relationships between these diseases, considering the information on the two age peaks for epilepsy onset in patients with autism.
About the Authors
G. V. Kuzmich
Svt. Luka’s Institute of Child Neurology and Epilepsy; Scientific and Practical Center for Mental Health of Children and Adolescents named after G.E. Sukhareva, Moscow City Department of Health.
Russian Federation
5 Nagornaya St., Troitsk, Moscow 108840; 21A 5th Donskoy proezd, Moscow 119334.
Russian Federation
5 Nagornaya St., Troitsk, Moscow 108840; 21A 5th Donskoy proezd, Moscow 119334.
A. N. Sinelnikova
Department of Normal Physiology, Medical Institute, Peoples’ Friendship University of Russia.
Russian Federation
6 Miklukho-Maklaya St., Moscow 117198.
Russian Federation
6 Miklukho-Maklaya St., Moscow 117198.
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Kuzmich G.V., Sinelnikova A.N. Comorbidity between epilepsy and autism from the point of view of ontogenesis. Russian Journal of Child Neurology. 2018;13(4):40-52. (In Russ.) https://doi.org/10.17650/2073-8803-2018-13-4-40-52
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