KOZHEVNIKOV–RASMUSSEN’S ENCEPHALITIS. A CASE REPORT
https://doi.org/10.17650/2073-8803-2014-9-1-52-57
Abstract
Kozhevnikov–Rasmussen's encephalitis (KRE) is a rare inflammatory brain disease characterized by severe intractable epilepsy and unilateral
progressive motor defect associated with controlateral hemispheric atrophy. Authors described clinical features, electroencephalography and magnetic resonance tomography data and course of the disease during 12 years of patient with adult onset KRE.
About the Authors
A. S. Kotov
Department of Neurology, Faculty for Graduate Training of Physicians, M.F. Vladimirsky Moscow Regional Research Clinical Institute
Russian Federation
Russian Federation
I. G. Rudakova
Department of Neurology, Faculty for Graduate Training of Physicians, M.F. Vladimirsky Moscow Regional Research Clinical Institute
Russian Federation
Russian Federation
K. Yu. Mukhin
Svt. Luka’s Institute of Child Neurology and Epilepsy, Moscow
Russian Federation
Russian Federation
M. B. Mironov
Svt. Luka’s Institute of Child Neurology and Epilepsy, Moscow
Russian Federation
Russian Federation
N. E. Kvaskova
Svt. Luka’s Institute of Child Neurology and Epilepsy, Moscow
Russian Federation
Russian Federation
A. A. Alihanov
Russian Children’s Clinical Hospital, Ministry of Health of Russia, Moscow
Russian Federation
Russian Federation
References
1. Алиханов А.А. Эпилептогенные воспалительные очаги. В кн.: Алиханов А.А. (ред.), Генералов В.О., Демушкина А.А. и др. Визуализация эпилептогенных поражений мозга у детей. М.: Издательский дом «Видар-М», 2009. С. 219–234.
2. Зенков Л.Р. Клиническая эпилептология (с элементами нейрофизиологии). М.: ООО «Медицинское информационное агентство», 2002.
3. К отов А.С., Рудакова И.Г., Мухин К.Ю. и др. Энцефалит Расмуссена. Описание двух клинических случаев. Рус журн дет неврол 2009;4(2):42–51.
4. Му хин К.Ю., Глухова Л.Ю. Синдром Расмуссена (хронический прогрессирующий очаговый энцефалит, энцефалит Расмуссена) и эпилепсия Кожевникова. В кн.: Мухин К.Ю., Петрухин А.С., Глухова Л.Ю. Эпилепсия. Атлас электро-клинической диагностики. М.: Альварес Паблишинг, 2004. С. 416–25.
5. Пет рухин А.С., Гуляева С.Е., Мухин К.Ю. Эпилепсия Кожевникова и энцефалит Расмуссена. В кн.: Петрухин А.С., Мухин К.Ю., Благосклонова Н.К., Алиханов А.А. Эпилептология детского возраста: Руководство для врачей. М.: Медицина, 2000. С. 117–31.
6. Bahi -Buisson N., Nabbout R., Plouin P. et al. Recent advances in pathogenic concepts and therapeutic strategies in Rasmussen's encephalitis. Rev Neurol (Paris) 2005;161(4):395–405.
7. Bahi- Buisson N., Villanueva V., Bulteau C. et al. Long term response to steroid therapy in Rasmussen encephalitis. Seizure 2007;16(6):485–92.
8. Granat a T. Rasmussen's syndrome. Neurol Sci 2003;24 Suppl 4:239–43.
9. Gray F. , Serdaru M., Baron H. et al. Chronic localized encephalitis (Rasmussen's) in an adult with epilepsia partialis continua. J Neurol Neurosurg Psychiatry 1987;50(6):747–51.
10. Hart Y. M., Cortez M., Andermann F. et al. Medical treatment of Rasmussen's syndrome (chronic encephalitis and epilepsy): effect of high-dose steroids or immunoglobulins in 19 patients. Neurology 1994;44(6):1030–6.
11. Jaillon- Riviere V., Dupont S., Bertran F. et al. Late onset Rasmussen's syndrome: clinical and therapeutic characteristics. Rev Neurol (Paris) 2007;163(5):573–80.
12. Mantegazz a R., Bernasconi P., Baggi F. et al. Antibodies against GluR3 peptides are not specific for Rasmussen's encephalitis but are also present in epilepsy patients with severe, early onset disease and intractable seizures. J Neuroimmunol 2002;131(1–2):179–85.
13. Rasmussen T ., Obszewski J., Lloyd-Smith D. Focal seizures due to chronic localized encephalitis. Neurology 1958;8(6):435–45.
14. Rogers S.W., Andrews P.I., Gahring L.C. et al. Autoantibodies to glutamate receptor GluR3 in Rasmussen's encephalitis. Science 1994;265(5172):648–51.
15. Takahashi Y., Mori H., Mishina M. et al. Autoantibodies and cell-mediated autoimmunity to NMDA-type GluRepsilon2 in patients with Rasmussen's encephalitis and chronic progressive epilepsia partialis continua. Epilepsia 2005;46 Suppl 5:152–8.
16. Villani F., Pi ncherle A., Antozzi C. et al. Adult-onset Rasmussen's encephalitis: anatomical-electrographic-clinical features of 7 Italian cases. Epilepsia 2006;47 Suppl 5:41–6.
17. Villani F., Spr eafico R., Farina L. et al. ositive response to immunomodulatory therapy in an adult patient with Rasmussen's encephalitis. Neurology 2001;56(2):248–50.
18. Von Oertzen J., Urbach H., Jungbluth S. et al. Standard magnetic resonance imaging is inadequate for patients with refractory focal epilepsy. J Neurol Neurosurg Psychiatry 2002;73(6):643–74.
19. Wiendl H., Bien C. G., Bernasconi P. et al. GluR3 antibodies: prevalence in focal epilepsy but no specificity for Rasmussen's encephalitis. Neurology 2001;57(8):1511–4.
Review
For citations:
Kotov A.S., Rudakova I.G., Mukhin K.Yu., Mironov M.B., Kvaskova N.E., Alihanov A.A. KOZHEVNIKOV–RASMUSSEN’S ENCEPHALITIS. A CASE REPORT. Russian Journal of Child Neurology. 2014;9(1):52-57. (In Russ.) https://doi.org/10.17650/2073-8803-2014-9-1-52-57
Views:
2810
Email this article 