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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Child Neurology</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Child Neurology</journal-title><trans-title-group xml:lang="ru"><trans-title>Русский журнал детской неврологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2073-8803</issn><issn publication-format="electronic">2412-9178</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">265</article-id><article-id pub-id-type="doi">10.17650/2073-8803-2018-13-3-45-56</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>ORIGINAL REPORTS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Efficacy and tolerability of brivaracetam in the treatment of epilepsy: literature review and own experience</article-title><trans-title-group xml:lang="ru"><trans-title>Эффективность и переносимость бриварацетама в лечении эпилепсии: обзор литературы и собственные данные</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Pylaeva</surname><given-names>O. A.</given-names></name><name xml:lang="ru"><surname>Пылаева</surname><given-names>О. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><italic>5 Nagornaya St., Troitsk, Moscow 108841</italic>; </p><p><italic>9 Akad. Anokhina St., 119579 Moscow</italic></p></bio><bio xml:lang="ru"><p><italic>108841 Москва, Троицк, ул. Нагорная, 5; </italic><italic>119579 Москва, ул. Акад. Анохина, 9</italic></p></bio><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Mukhin</surname><given-names>K. Yu.</given-names></name><name xml:lang="ru"><surname>Мухин</surname><given-names>К. Ю.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><italic>5 Nagornaya St., Troitsk, Moscow 108841</italic>; </p><p><italic>9 Akad. Anokhina St., 119579 Moscow</italic></p></bio><bio xml:lang="ru"><p><bold>Константин Юрьевич Мухин</bold></p><p><italic>108841 Москва, Троицк, ул. Нагорная, 5; </italic><italic>119579 Москва, ул. Акад. Анохина, 9</italic></p></bio><email>center@epileptologist.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Svt. Luka’s Institute of Child Neurology and Epilepsy</institution></aff><aff><institution xml:lang="ru">ООО «Институт детской неврологии и эпилепсии им. Свт. Луки»</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Svt. Luka’s Institute of Child and Adult Neurology</institution></aff><aff><institution xml:lang="ru">ООО «Институт детской и взрослой неврологии и эпилепсии имени Свт. Луки»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2018-07-15" publication-format="electronic"><day>15</day><month>07</month><year>2018</year></pub-date><volume>13</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>45</fpage><lpage>55</lpage><history><date date-type="received" iso-8601-date="2018-11-29"><day>29</day><month>11</month><year>2018</year></date><date date-type="accepted" iso-8601-date="2018-11-29"><day>29</day><month>11</month><year>2018</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2018, ABV-Press</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2018, АБВ-пресс</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="en">ABV-Press</copyright-holder><copyright-holder xml:lang="ru">АБВ-пресс</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://rjdn.abvpress.ru/jour/about/editorialPolicies</ali:license_ref></license></permissions><self-uri xlink:href="https://rjdn.abvpress.ru/jour/article/view/265">https://rjdn.abvpress.ru/jour/article/view/265</self-uri><abstract xml:lang="en"><p/></abstract><trans-abstract xml:lang="ru"><p/></trans-abstract><kwd-group xml:lang="en"><kwd>epilepsy</kwd><kwd>intractable epilepsy</kwd><kwd>drug-resistant epilepsy</kwd><kwd>focal epilepsy</kwd><kwd>focal epileptic seizures</kwd><kwd>antiepileptic drug</kwd><kwd>brivaracetam</kwd><kwd>efficacy</kwd><kwd>tolerability</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>эпилепсия</kwd><kwd>труднокурабельная эпилепсия</kwd><kwd>фармакорезистентная эпилепсия</kwd><kwd>фокальная эпилепсия</kwd><kwd>фокальные эпилептические приступы</kwd><kwd>антиэпилептический препарат</kwd><kwd>бриварацетам</kwd><kwd>эффективность</kwd><kwd>переносимость</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Karlov V.A., Vlasov P.N., Zhidkova I.A. et al. 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