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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Child Neurology</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Child Neurology</journal-title><trans-title-group xml:lang="ru"><trans-title>Русский журнал детской неврологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2073-8803</issn><issn publication-format="electronic">2412-9178</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">236</article-id><article-id pub-id-type="doi">10.17650/2073-8803-2017-12-4-56-62</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>CLINICAL OBSERVATIONS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Neuromyelitis optica spectrum disorder in childhood (a case report)</article-title><trans-title-group xml:lang="ru"><trans-title>Расстройство из спектра оптиконевромиелита в детском возрасте (клинический случай)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kotov</surname><given-names>A. S.</given-names></name><name xml:lang="ru"><surname>Котов</surname><given-names>А. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>61/2 Shchepkina St., Moscow 129110.</p></bio><bio xml:lang="ru"><p>129110 Москва, ул. Щепкина, 61/2.</p></bio><email>alex-013@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tokareva</surname><given-names>Yu. V.</given-names></name><name xml:lang="ru"><surname>Токарева</surname><given-names>Ю. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>61/2 Shchepkina St., Moscow 129110.</p></bio><bio xml:lang="ru"><p>129110 Москва, ул. Щепкина, 61/2.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Lutsik</surname><given-names>V. N.</given-names></name><name xml:lang="ru"><surname>Луцик</surname><given-names>В. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>61/2 Shchepkina St., Moscow 129110.</p></bio><bio xml:lang="ru"><p>129110 Москва, ул. Щепкина, 61/2.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Panteleeva</surname><given-names>M. V.</given-names></name><name xml:lang="ru"><surname>Пантелеева</surname><given-names>М. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>61/2 Shchepkina St., Moscow 129110.</p></bio><bio xml:lang="ru"><p>129110 Москва, ул. Щепкина, 61/2.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shatalin</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Шаталин</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>61/2 Shchepkina St., Moscow 129110.</p></bio><bio xml:lang="ru"><p>129110 Москва, ул. Щепкина, 61/2.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Mukhina</surname><given-names>E. V.</given-names></name><name xml:lang="ru"><surname>Мухина</surname><given-names>Е. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>61/2 Shchepkina St., Moscow 129110.</p></bio><bio xml:lang="ru"><p>129110 Москва, ул. Щепкина, 61/2.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bunak</surname><given-names>M. S.</given-names></name><name xml:lang="ru"><surname>Бунак</surname><given-names>М. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>61/2 Shchepkina St., Moscow 129110.</p></bio><bio xml:lang="ru"><p>129110 Москва, ул. Щепкина, 61/2.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Andryukhina</surname><given-names>O. M.</given-names></name><name xml:lang="ru"><surname>Андрюхина</surname><given-names>О. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>61/2 Shchepkina St., Moscow 129110.</p></bio><bio xml:lang="ru"><p>129110 Москва, ул. Щепкина, 61/2.</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">M.F. Vladimirsky Moscow Regional Research Clinical Institute.</institution></aff><aff><institution xml:lang="ru">ГБУЗ МО «Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского».</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2017-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2017</year></pub-date><volume>12</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>56</fpage><lpage>62</lpage><history><date date-type="received" iso-8601-date="2018-01-19"><day>19</day><month>01</month><year>2018</year></date><date date-type="accepted" iso-8601-date="2018-01-19"><day>19</day><month>01</month><year>2018</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2017, ABV-Press</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2017, АБВ-пресс</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="en">ABV-Press</copyright-holder><copyright-holder xml:lang="ru">АБВ-пресс</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://rjdn.abvpress.ru/jour/about/editorialPolicies</ali:license_ref></license></permissions><self-uri xlink:href="https://rjdn.abvpress.ru/jour/article/view/236">https://rjdn.abvpress.ru/jour/article/view/236</self-uri><abstract xml:lang="en"><p>Neuromyelitis optica spectrum disorder is an inflammatory demyelinating disease of the central nervous system with selective damage to the optic nerves and spinal cord. The clinical case of a child 11 years old and its course throughout the year, with an onset in the form of an episode of visual impairment with signs of a previously developed partial atrophy of the optic nerves of both eyes and a manifestation of retrobulbar neuritis on the left eye is considered in the article. Repeatedly conducted magnetic resonance examination revealed a pattern of focal lesion of the left and then of the right optic nerve with a violation of the integrity of the blood brain barrier and an extended focus in the structure  of the spinal cord of the cervical spine. The blood test for antibody to aquaporin-4 was positive. Optical coherence tomography revealed decrease in the thickness of the peripapillary fibers of the retina in all quadrants in both eyes, which indicates a partial atrophy of the optic nerves  of both eyes, as a result of repeatedly transferred retrobulbar neuritis in both eyes.</p></abstract><trans-abstract xml:lang="ru"><p/></trans-abstract><kwd-group xml:lang="en"><kwd>Devic’s disease</kwd><kwd>neuromyelitis optica spectrum disorder</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>болезнь Девика</kwd><kwd>расстройство из спектра оптиконевромиелита</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Котов А.С., Андрюхина О.М., Матюк Ю.В. и др. Оптический неврит и миелит у подростка: оптикомиелит Девика или рассеянный склероз? Неврологический журнал 2015;20(6):35–40. [Kotov A.S., Andryukhina O.M., Matyuk Yu.V. et al. 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