Russian Journal of Child NeurologyRussian Journal of Child NeurologyРусский журнал детской неврологии2073-88032412-9178Publishing House ABV Press19010.17650/2073-8803-2017-12-1-21-35ORIGINAL REPORTSОРИГИНАЛЬНЫЕ СТАТЬИEpilepsy with electrical status epilepticus during slow-wave sleep with a focus on electroencephalographic criteriaЭпилепсия с электрическим эпилептическим статусом в фазу медленного сна с фокусом на электроэнцефалографические критерииMukhinK. Yu.МухинК. Ю.
Russian Federation

6 Svetlaya St., Puchkovo Village, Pervomayskoe Settlement, Moscow 143397, Russia

Россия, 143397 Москва, пос. Первомайское, дер. Пучково, ул. Светлая, 6

center@epileptologist.ruGlukhovaL. Yu.ГлуховаЛ. Ю.
Russian Federation

6 Svetlaya St., Puchkovo Village, Pervomayskoe Settlement, Moscow 143397, Russia

Россия, 143397 Москва, пос. Первомайское, дер. Пучково, ул. Светлая, 6

MakievskayaE. R.МакиевскаяЕ. Р.
Russian Federation

21A 5th Donskoy Proezd, Moscow 119334, Russia

Россия, 119334 Москва, 5-й Донской проезд, 21А

Svt. Luka’s Institute of Child Neurology and EpilepsyООО «Институт детской неврологии и эпилепсии им. Святителя Луки»G.E. Sukhareva Scientific-Practical Center of Mental Health of Children and Adolescents, Moscow Healthcare DepartmentГБУЗ «Научно-практический центр психического здоровья детей и подростков им. Г.Е. Сухаревой Департамента здравоохранения г. Москвы»1501201712121350704201707042017Copyright ©; 2017, ABV-PressCopyright ©; 2017, АБВ-пресс2017ABV-PressАБВ-прессhttps://rjdn.abvpress.ru/jour/about/editorialPolicieshttps://rjdn.abvpress.ru/jour/article/view/190

The authors present a detailed literature review, devoted to epilepsy with electrical status epilepticus during slow-wave sleep (ESES), as well as own data. The issues of classification, etiology, ESES diagnostic criteria, aproaches to therapy and prognosis are discussed in the article. Authors pay particular attention to the description of electroencephalographic abnormalities in patients with ESES including changes in electroencephalogram (EEG) during seizures and in the intetictal period (first of all during sleep). EEG during sleep is crucial in case of ESES, it is necessary for diagnosis. 20 % of the patients have no epileptic seizures; the diagnosis is based on the EEG results and neuropsychological testing. Continuous spike-and- wave epileptiform activity on EEG during slow-wave sleep is a compulsory diagnostic criterion for ESES. This activity defines the clinical spectrum of cognitive and behavioral discorders in patients with this disease.

В статье представлен подробный обзор литературы, посвященной эпилепсии с электрическим эпилептическим статусом в фазу медленного сна (ЭЭСМ), и собственные данные. Рассматриваются вопросы классификации, этиологии, диагностические критерии ЭЭСМ, дифференциальный диагноз, подходы к терапии и прогноз. Особое внимание уделяется описанию электроэнцефалографических нарушений у пациентов с ЭЭСМ, включая изменения на электроэнцефалограмме (ЭЭГ) во время приступов и в межприступном периоде (прежде всего во сне). ЭЭГ сна имеет определяющее значение при ЭЭСМ и необходима для установления диагноза. У 20 % больных эпилептические приступы отсутствуют, и диагноз устанавливается на основании результатов исследования ЭЭГ и нейропсихологического тестирования. Обязательным диагностическим признаком ЭЭСМ является продолженная пик-волновая эпилептиформная активность на ЭЭГ в фазу медленного сна, определяющая клинический спектр когнитивных и поведенческих нарушений при данном заболевании.

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